- apurinic site
- апуриновый сайт, АП-сайт
English-Russian Biotechnology Glossary. A. F. Valikhov, V. V. Kolotvin, O. A. Legonkova, I. A. Rogov, Thomas Creamer. 2007.
apurinic site
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Site AP — Un site AP est un emplacement de l ADN où la base (normalement attachée) est manquante.En l absence de réparation, il peuvent mener à une rupture simple brin. Lors de la réplication, ils mènent très souvent à une mutation. Un site AP (site… … Wikipédia en Français
DNA-(apurinic or apyrimidinic site) lyase — Identifiers EC number 4.2.99.18 CAS number 61811 29 8 … Wikipedia
AP site — An AP site (meaning apurinic and apyrimidinic) is a location in DNA that have neither a purine nor pyrimidine base, usually due to DNA damage.If left unrepaired AP sites can lead to mutation during semiconservative replication as a random… … Wikipedia
Mutagenesis — (pronounced /mjuːtəˈdʒɛnɪsɪs/) is a process by which the genetic information of an organism is changed in a stable manner, resulting in a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be… … Wikipedia
Depurination — In molecular genetics, depurination is an alteration of DNA in which the purine base (adenine or guanine) is removed from the deoxyribose sugar by hydrolysis of the beta N glycosidic link between them. After depurination, an apurinic site is… … Wikipedia
Mutation — For other uses, see Mutation (disambiguation). Part of the Biology series on Evolution … Wikipedia
APEX1 — APEX nuclease (multifunctional DNA repair enzyme) 1, also known as APEX1, is a human gene. PBB Summary section title = summary text = Apurinic/apyrimidinic (AP) sites (also called abasic sites ) occur frequently in DNA molecules by spontaneous… … Wikipedia
AP endonuclease — An AP endonuclease is an enzyme that cuts a strand of DNA on the 5 side of an AP (apurinic/apyrimidinic) site, as the first step in DNA base excision repair (BER).AP endonucleases are divided into two families based on their homology to the… … Wikipedia
DNA polymerase beta — Polymerase (DNA directed), beta PDB rendering based on 1bno … Wikipedia
Activation-Induced (Cytidine) Deaminase — (AID) is a 24 kDa enzyme that removes the amino group from the cytidine base in DNA.AID is currently thought to be the master regulator of secondary antibody diversification. It is involved in the initiation of three separate immunoglobulin (Ig)… … Wikipedia
AP — is a versatile abbreviation. It serves in cardiology to abbreviate angina pectoris (AP) and arterial pressure (AP). In endocrinology, it stands for the anterior pituitary (AP). And in anatomy, AP means anteroposterior, i.e., from front to back. * … Medical dictionary
